Impact of Age on the Trace Elements Levels in Human Immunodeficiency Virus Patients on Highly Active Antiretroviral Therapy (AART) Attending Federal Medical Centre Owerri, Imo State, Nigeria

Authors

  • Dominic Chinedu Ejiofor David Umahi Federal University, of Health Sciences, Uburu Ebonyi State
  • Edward-Ejiofor Bridget Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Imo State University, Owerri Nigeria
  • Azunna Uchenna Department of Human Physiology, College of Basic Medicine, Abia State University Uturu, Abia State Nigeria
  • Iheukwumere Barry Chinedu Department of Human Physiology, College of Basic Medicine, Abia State University Uturu, Abia State Nigeria
  • Ngwuta Victor Sochima Department of Human Physiology, Faculty of Basic Medical Sciences, David Umahi Federal University of Health Sciences, Uburu Ebonyi State, Nigeria
  • Ndiweogu Chukwuebuka Junior Department of Human Physiology, Faculty of Basic Medical Sciences, David Umahi Federal University of Health Sciences, Uburu Ebonyi State, Nigeria
  • Ideyi Chikezie Department of Internal Medicine, Federal University Teaching Hospital Owerri Nigeria
  • Obi, Augustine Uchechukwu Department of Human Anatomy and Neurobiology, Faculty of Basic Medical Sciences, Imo State University Owerri Nigeria
  • Onwuka, Kelechi Collins Department of Human Physiology, College of Basic Medicine, Abia State University Uturu, Abia State Nigeria
  • Obialor Nnamdi Ambrose Department of Human Anatomy and Neurobiology, Faculty of Basic Medical Sciences, Imo State University Owerri Nigeria
  • Obi Dorin Ifunanyachukwu Department of Internal Medicine, Faculty of Clinical Medicine, Chukwuemeka Odumegwu Ojukwu University, Anambra State, Nigeria
  • Ibeh Chinelo Favour Department of Medical Laboratory Sciences, Abia State University Uturu, Abia State, Nigeria

DOI:

https://doi.org/10.33003/sajols-2025-0303-18

Abstract

Advancing age is characterized by impaired pharmacodynamic and pharmacokinetic changes. Therefore, this study aimed to assess the impact of age on trace element levels in Human Immunodeficiency Virus patients on Highly Active Antiretroviral Therapy (HAART). A total of 196 HIV-positive patients in the age ranges of 20-29, 30-39, 40-49, 50-59, 60-69, and 70-79 years old who are on HAART were recruited for the study. Determinations of HIV status and plasma trace element levels of the participants were performed using standard procedures. Results obtained from the study showed that zinc, selenium, and iron levels were most pronounced among HAART subjects in the age ranges of 20-29 and 30-39 years old, but declined in HAART subjects in the age ranges of 60-69 and 70-79 years old. In conclusion, it can be deduced from this study that HAART is most effective in younger individuals.

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Published

2025-09-30

How to Cite

Ejiofor, D. C., Edward-Ejiofor, B., Azunna, U., Iheukwumere Barry, C., Ngwuta, V. S., Ndiweogu , C. J., Ideyi , C., Obi, , A. U., Onwuka, , K. C., Obialor , N. A., Obi , D. I., & Ibeh , C. F. (2025). Impact of Age on the Trace Elements Levels in Human Immunodeficiency Virus Patients on Highly Active Antiretroviral Therapy (AART) Attending Federal Medical Centre Owerri, Imo State, Nigeria. Sahel Journal of Life Sciences FUDMA, 3(3), 145–147. https://doi.org/10.33003/sajols-2025-0303-18

Issue

Vol. 3 No. 3 (2025): Sahel Journal of Life Sciences FUDMA (SAJOLS)

Section

Research Articles